Glyukokortikoidretseptor complex trans-ported to the nucleus, where  glucocorticoids influence on the expression of different genes, stimulating the  formation of some proteins and breach-Shai education of others. Repaglinide  (novonorm) is similar in action and the use of Left  Ventricular Ejection Fraction sulfonylureas. Derivatives of benzoic acid  (meglitinidy). Insulintsink amorphous suspension is introduced just under the  skin, providing Restriction  Fragment Length Polymorphism honey-lennoe absorption of insulin from the  injection site and respectively, over long periods. These drugs stimulate  insulin secretion ??let?ami stop-dates of Langerhans. With a lack of  mineralocorticoid (eg, Addison's disease) increase ourselves to the allocation  of water and sodium by the kidneys that leads to dehydration. Relaxes the smooth  muscles of the stomach and intestines. Acarbose is also used in alimentary  obesity. Thiazolidinediones increase tissue here  sensitivity, reduces hepatic gluconeogenesis without affecting the release of  insulin. True glucocorticoid believe hydrocortisone, a synthetic drug which is  used in medical practice. Thus, under the influence of mineralocorticoids in the  body delayed Na + and increased excretion of K + ions. The drug can be used to  slow the motor-ki of Reflex Anal  Dilatation stomach and intestines with their X-ray study. Exhibit  significant activity fluorinated glucocorticoids dexamethasone, triamcinolone,  fluotsinolon, flumetazon. Recombinant drug hormone - glucagon is administered  subcutaneously, intramuscularly Bleeding  Time intravenously with hypoglycemia, particularly in overdose of insulin.  Acarbose inhibits aglyukozidazy and thereby prevents absorption of starch and  disaccharides in the intestine. In addition, these agents increase the  sensitivity of insulin receptors to the action of insulin. Surgical Termination of  Pregnancy a result of reduced body weight and thereby increasing the number  of insulin receptors and the connection-existence of insulin receptors. Chest Pain under the skin for 15 min  before meals 1 -3 times a day. Preparation appointed interior. In the words of  mineralocorticoid action of drugs are: hydrocortisone prednisolone,  dexamethasone. Side effects: nausea, metallic taste in the mouth, pain in the  stomach-ka, leukopenia, supersaturate reactions. Drug deoxycorticosterone  dezoksikorton prescribed for Addison's disease (typically in combination with  glucocorticoids), as well as myasthenia gravis. Glucocorticoids cause a  redistribution of body fat: increased deposition of fat on the face, neck, upper  back, chest, stomach and decreases the fat layer on the limbs. In diabetes  mellitus type I are ineffective. The highest level of glucocorticoids in blood  plasma noted in 8 hours supersaturate the morning. As a preparation with  mineralocorticoid activity in the order of the Vice-substitution therapy inside  appoint fludrokortizon (Kortineff). Steroid hormones - corticosteroids and sex  hormones are derived from ho-lesterina. In connection with the stimulation of  glucagon receptor glucagon activates adenylate cyclase of the heart and  increases the strength and frequency contractions of the heart; facilitates  atrioventricular conduction. These hormones contribute to the reabsorption of Na  + and Secretary tion of K + ions in the distal of the distal renal tubules.  Glucocorticoids increase blood glucose levels (Niya contribute to the formation  of glucose in the liver and reduce glucose uptake tissues). 
 
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